C. I. 75640; Kaempferol; 3, 5, 7, 4-Tetrahydroxyflavone; 3, 5, 7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 2-(2, 4-dihydroxyphenyl)-5, 7-dihydroxy-4H-chromen-4-one
Light yellow needle crystal
Fruit of kaempferia galanga L.
90%, 95%, 98% by HPLC
Certificate of Analysis
Purple -red fine powder
100% pass through 80 mesh sieve
Loss on drying(5h at 105° C)
Ash(3h at 600° C)
Heavy metals(as Pb)
Eur. Pharm. 2000
Total bacterial count
Yeast & Mould
Escherichia coli presence
Max. 100cfu /g
Functions and Applications
1. Kaempferol was found to be active in promoting Opossum Kidney cell growth. Kaempferol stimulates kidney cells proliferation and increases secretion of bone growth factor. Kaempferol may serve to stimulate kidney repair and up-regulate bone formation and may be useful in treating chronic kidney disease and osteoporosis.
2. Kaempferol can inhibit the apoptosis induced by H202 in neonatal rat cardionyocytes. The protective effects could be related to their antiocidant activity and its ability to regulate the expression of Bcl-2, Bax, Caspase-3 protein.
3. Kaempferol is a blocker of voltagegated potassium channels in pyramidal neurons of rat hippocampus. The electrophysiological effects of kaempferol may be one mechanism of its protective effects on rat hippocampal neurons in acutely transient hypoxia.
4. Kaempferol owe to the strong antioxidant properties, can scavenge superfluous superoxide free radicals in human body, preventing DNA and cells from oxidative damage. It show pharmacological effects in anti-tumour, anti-inflammation and anti-senility, etc.
5. Kaempferol has the effect of anti-epilepsy, antispasmodic, anthelone, antiulcer, choleretic, diuretic activity and relieving cough.